940704

TissueFab^® photoinitiator

LAP, low endotoxin

• Synonym(s): Lithium phenyl-2,4,6-trimethylbenzoylphosphinate
• Empirical Formula (Hill Notation): C₁₆H₁₆LiO₃P
• CAS Number: 85073-19-4
• Molecular Weight: 294.21
• MDL number: MFCD29472537
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• description: grade: biomedical research grade
• Assay: ≥95% (HPLC)
• form: solid
• impurities: Endotoxin: < 50 EU/g ; ; Bioburden (Fungal): < 5 CFU/100MG ; ; Bioburden (total aerobic): <5CFU/100MG
• storage temp.: 2-8°C
• SMILES string: CC1=C(C(P(C2=CC=CC=C2)(O[Li])=O)=O)C(C)=CC(C)=C1

Description

General description

Rethink your bioinks with TissueFab^®
About the material:
High quality, low endotoxin Lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) photoinitiator
Crosslinking parameters:
*Suitable for polymerizing bioinks, hydrogels, and other polymeric materials
* Photocrosslinking at 405 nm (visible light)
The low endotoxin TissueFab^® LAP photoinitiator is a cytocompatible, Type I photoinitator utilized for the polymerization of water-soluble hydrogels, bioinks, and other polymeric materials. It is preferred in biological applications over other photoinitatiors such as Irgacure 2959 (I2959) due to its superior water solubility, faster poymerization kinetics, and absorption at 405nm which allows for photocrosslinking under more cell-friendly conditions. The TissueFab^® LAP photoinitiator is optimized for cell viability, with an endotoxin level below 50 EU/ml, making it ideal for a variety of biomedical applications.

Application

*3D bioprinting
*3D cell encapsulation and cell culture
*Hydrogels
*Medical device coatings
* Drug delivery vehicles

Features and Benefits

Superior Water Solubility: Enhances ease of use in aqueous environments, improving handling and application. Biocompatible: Safe for use in biological contexts, promoting cell health and viability.
Sensitive to Visible Light: Allows for polymerization with visible light, offering versatility beyond traditional UV light sources. Faster Polymerization Kinetics: Enables quicker cell encapsulation compared to alternatives, crucial for efficient bioprinting processes.

Legal Information

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable