702730

tert-Butylchlorodiphenylsilane solution

1 M in methylene chloride

• Empirical Formula (Hill Notation): C₁₆H₁₉ClSi
• CAS Number: 58479-61-1
• Molecular Weight: 274.86
• MDL number: MFCD00000497
• UNSPSC Code: 12352002
• PubChem Substance ID: 329762399
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 100
• concentration: 1 M in methylene chloride
• bp: 40 °C
• density: 1.249 g/mL at 25 °C
• SMILES string: CC(C)(C)[Si](Cl)(c1ccccc1)c2ccccc2
• InChI: 1S/C16H19ClSi/c1-16(2,3)18(17,14-10-6-4-7-11-14)15-12-8-5-9-13-15/h4-13H,1-3H3
• InChI key: MHYGQXWCZAYSLJ-UHFFFAOYSA-N

Description

Application

tert-Butylchlorodiphenylsilane can be used to prepare 1-benzyloxy-3-(tert-butyldiphenylsilyloxy)propan-2-ol, a key intermediate for the synthesis of mono-O-protected pyrimidine acyclic nucleosides.

Safety Information

• Pictograms: GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H314,H335,H336,H351
• Precautionary Statements: P202 - P261 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Storage Class Code: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves