SMB00607

Amoxicillin trihydrate: potassium clavulanate (4:1)

• Sinônimo(s): Amoxicillin Trihydrate: Potassium Clavulanate
• Código UNSPSC: 51285005
• NACRES: NA.85

Propriedades

• Formulário: powder
• Nível de qualidade: 200
• condição de armazenamento: (Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.)
• cor: white to yellow
• espectro de atividade do antibiótico: Gram-negative bacteria; Gram-positive bacteria
• Modo de ação: cell wall synthesis | interferes
• temperatura de armazenamento: 2-8°C

Descrição

Descrição geral

Amoxicillin trihydrate is a semisynthetic antibiotic, that is used as a medicine.

Aplicação

Amoxicillin trihydrate: potassium clavulanate (4:1) has been used to study its effect on the viral déjà vu disease (neonatal intracerebral (i.c.) infection) in mice model.

Ações bioquímicas/fisiológicas

Amoxicillin trihydrate is a broad-spectrum, β-lactam antibiotic. It inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. Since amoxicillin is degraded by β-lactamases, it does not show activity against bacteria which produce these enzymes.

Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.

Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by β-lactamase enzymes. This increases amoxicillin′s antibacterial activity against bacteria normally resistant to β-lactam antibiotics.

Embalagem

1G

Componentes

Material is a powdered mixture of 4 parts amoxicillin trihydrate to 1 part potassium clavulanate.

Armazenamento e estabilidade

Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.

Informações de segurança

• Pictogramas: GHS02,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H228,H252,H317,H334
• Declarações de precaução: P210 - P235 - P240 - P241 - P280 - P302 + P352
• Classificações de perigo: Flam. Sol. 2 - Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1
• Perigos de suplementos: EUH014,EUH044
• Código de classe de armazenamento: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable