271012

N,N-Dimethylacetamide

anhydrous, 99.8%

• Synonym(s): DMAc
• Linear Formula: CH₃CON(CH₃)₂
• CAS Number: 127-19-5
• Molecular Weight: 87.12
• Beilstein: 1737614
• EC Number: 204-826-4
• MDL number: MFCD00008686
• UNSPSC Code: 12352111
• PubChem Substance ID: 57648218
• NACRES: NA.21
• Grade: anhydrous
• Assay: 99.8%
• Bp: 164.5-166 °C (lit.)
• Vapor pressure: 2 mmHg ( 25 °C); 4 mmHg ( 38 °C)

Properties

• grade: anhydrous
• Quality Level: 200
• vapor density: 3 (vs air)
• vapor pressure: 2 mmHg ( 25 °C); 4 mmHg ( 38 °C)
• Assay: 99.8%
• form: liquid
• autoignition temp.: 914 °F
• expl. lim.: 1.8 %, 100 °F; 11.5 %, 160 °F
• impurities: <0.005% water
• evapn. residue: <0.001%
• refractive index: n20/D 1.437 (lit.)
• pH: 4 (20 °C, 200 g/L)
• bp: 164.5-166 °C (lit.)
• mp: −20 °C (lit.)
• density: 0.937 g/mL at 25 °C (lit.)
• SMILES string: CN(C)C(C)=O
• InChI: 1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
• InChI key: FXHOOIRPVKKKFG-UHFFFAOYSA-N

Description

Application

N,N-Dimethylacetamide may be used as a solvent in the following processes:

• Palladium (II) acetate-butyldi-1-adamantylphosphine catalyzed arylation of 2-isobutylthiazole with chlorobenzene to form 5-phenyl-2-isobutylthiazole.
• Synthesis of β-, γ-, and δ-metallo ester intermediates that can react with acid chlorides to form γ-, δ-, and ε-keto esters.
• Synthesis of (R)-(-)-methyl 1,1′-binaphthyl-2,2′-diylphosphate that can be used as a precursor for preparing (R)-(+)-1,1′-binaphthalene-2,2′-diol.

Packaging

View returnable container options.

Other Notes

The article number 271012-4X2L will be discontinued. Please order the single bottle 271012-2L which is physically identical with the same exact specifications.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H312 + H332,H319,H360D
• Precautionary Statements: P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): 147.2 °F - closed cup
• Flash Point(C): 64 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves