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Merck

PCC300C15C

Millipore

Pellicon® Capsule with Ultracel® Membrane

C Screen, 1.5 m2 AseptiQuik® G connectors

Synonym(s):

Pellicon® Capsule with Ultracel® Membrane

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About This Item

UNSPSC Code:
23151806

Key Documents

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material

EPDM rubber seal
PPO/PS blend (core)
PPO/PS blend housing
TPE seal
composite regenerated cellulose (CRC) membrane
epoxy adhesive
polyester screen
polypropylene screen
polyurethane adhesive

Quality Level

400

sterility

sterile; γ-irradiated

product line

Pellicon®

feature

holdup volume 456 mL (in feed channel)
holdup volume 741 mL (in permeate channel)

packaging

package of 1

parameter

max. inlet pressure at 75 psi (5.1 bar) and 4-30 °C
 max. transmembrane pressure at 45 psi (3.1 bar) and 4-30 °C
4-6 L/min-m2 flow rate

technique(s)

ultrafiltration: suitable

diam.

10.3 cm (4.1 in.)

filtration area

1.5 m2

screen size

, Type C screen (coarse screen)

size

43.7 cm (17.2 in.) , Length

impurities

≤5 ppm Meets TOC (in retentate effluent, after a WFI flush of 20 L/m²)

matrix

Ultracel®

pore size

300 kDa

pH range

2-13

storage temp.

15-25°C

General description

The Pellicon® Capsule is the first of its kind -- a true single-use TFF device that comes ready to process in minutes. Self-contained, it employs an easy-to-use, holderless format and is supplied sterilized by irradiation.
Feed: AseptiQuik® G Connector
Permeate: AseptiQuik® G Connector
Retentate: AseptiQuik® G Connector
Permeate: AseptiQuik® G Connector

Application

Viral Gene Therapies, Vaccines, Concentration, Diafiltration, Buffer exchange, Protein purification, mRNA

Features and Benefits

  • Plug ′n play, holderless design - easy to install, safe to remove
  • Gamma Sterilized and preseravtive-free - ready to process in minutes
  • True single-use, self-contained capusle - fast, safe, and flexible batch turnaround
  • Proven Ultracel® membrane and C screen - high recovery, superior mass transfer, solvent resistance
  • Pellicon® TFF proven performance - true linear scalability within Pellicon® TFF families

Packaging

A foam clamshell is inserted over the end caps on both ends of the capsule which is then double-bagged and vacuum sealed. The double-bagged capsule is placed on a tray and then individually boxed.

Other Notes

The Emprove® Program complements the product portfolio through

  • Comprehensive documentation to support qualification, risk assessment and process optimization needs.
  • Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
  • Convenient 24/7 access to up-to-date product information.

Legal Information

AseptiQuik is a registered trademark of Colder Products Company
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

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