SML3616
Kazinol U
≥95% (HPLC)
Synonym(s):
(+)-Kazinol U, 4-[(2S)-3,4-Dihydro-7-hydroxy-2H-1-benzopyran-2-yl]-3-(3-methyl-2-buten-1-yl)-1,2-benzenediol
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About This Item
Empirical Formula (Hill Notation):
C20H22O4
CAS Number:
Molecular Weight:
326.39
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
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Quality Level
Assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Anti-melanogenic in mouse and human melanoma cells through the induction of AMPK and MAPK phosphorylation
Kazinol U is prenylated flavan isolated from an extract of Broussonetia kazinoki Sieb (paper mulberry) that exhibits anti-melanogenic activity in mouse and human melanoma cells through the induction of AMPK and MAPK phosphorylation. Kazinol U inhibits tyrosinase activity and melanin synthesis through the reduction of MITF expression. It suppresses melanogenesis in a zebrafish model. Kazinol U displays phytoestrogenic and anti-inflammatory activities. Kazinol U exhibits cytoprotective activities against cytokine-induced apoptotic cell death.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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