SAB5702099

Anti-Integrin alpha 5 (ITGA5/CD49E) Antibody

rabbit monoclonal, 8F2O6

• Synonym(s): CD49e,FNRA,VLA-5,VLA5A,Integrin alpha 5,ITGA5
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• Product Name: Anti-Integrin alpha 5 (ITGA5/CD49e) Antibody, clone 8F2O6, Rabbit Monoclonal,
• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 8F2O6, monoclonal
• form: liquid
• species reactivity: human, rat, rat
• concentration: 0.44 mg/mL
• technique(s): flow cytometry: 1:50 - 1:200; immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: HQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLPYGTAMEKAQLKPPATSDA
• UniProt accession no.: P08648
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ITGA5(3678)

Description

General description

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 950-1049 of human Integrin alpha 5 (ITGA5/CD49e) (P08648).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC, IP, FC

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1