SAB5701885

Anti-Phospho-FAK-Y576/577 antibody produced in rabbit

• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: rat, mouse, human
• concentration: 2.91 mg/mL
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q05397
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr576/pTyr577)
• Gene Information: human ... PTK2(5747)

Description

General description

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015]

Immunogen

A synthetic phosphorylated peptide around Y925 of human FAK (NP_722560.1).

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable