5.05222

RuBi-Nicotine

• Synonym(s): RuBi-Nicotine, Bis(2,2′-bipyridine-N,N′)bis(S-nicotine-N1) ruthenium(2+) dichloride complex Bis(2,2ʹ-bipyridine-N,Nʹ)bis(S-nicotine-N1) ruthenium(2+) dichloride complex , Nicotinic Cholinergic Receptor Agonist, RuBi-Nicotine, nAChR Receptor Agonist, RuBi-Nico
• Empirical Formula (Hill Notation): C₄₀H₄₄Cl₂N₈Ru
• CAS Number: 1256362-30-7
• Molecular Weight: 808.81
• MDL number: MFCD22989497
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥98% (NMR)
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: deep orange
• solubility: H₂O: 100 mM
• storage temp.: −20°C
• SMILES string: [Ru+2]85([NH]9=CC=CC=C9C%10=CC=CC=[NH]%108)([NH]6=CC=CC=C6C7=CC=CC=[NH]75)([NH]3=CC=CC(=C3)[C@H]4N(CCC4)C)[NH]1=CC=CC(=C1)[C@H]2N(CCC2)C.[Cl-].[Cl-]
• InChI: 1S/2C10H14N2.2C10H8N2.2ClH.Ru/c2*1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*1-3-7-11-9(5-1)10-6-2-4-8-12-10;;;/h2*2,4,6,8,10H,3,5,7H2,1H3;2*1-8H;2*1H;/q;;;;;;+2/p-2/t2*10-;;;;;/m00...../s1
• InChI key: BQXVYFYPLMVART-ZPFSJBFKSA-L

Description

General description

A highly water soluble Ruthenium-bisbipyridine-caged nicotine that can be un-caged by blue and green light. Rapid nicotine release (<20 ns) and fast biological effects in vivo.

Biochem/physiol Actions

Primary Target
nAChR

Warning

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Filevich, O., et al. 2010. J. Inorg. Biochem.104, 51.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H301 - H310 - H410
• Precautionary Statements: P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable