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Merck

T8441

Sigma-Aldrich

L-Threonine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonym(s):

(2S,3R)-2-Amino-3-hydroxybutyric acid

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About This Item

Linear Formula:
CH3CH(OH)CH(NH2)CO2H
CAS Number:
72-19-5
Molecular Weight:
119.12
Beilstein:
1721646
EC Number:
200-774-1
MDL number:
MFCD00064270
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24900531
NACRES:
NA.26

Key Documents

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Product Name

L-Threonine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

biological source

non-animal source

Quality Level

300

Agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

product line

BioXtra

Assay

99.0-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

256 °C (dec.) (lit.)

solubility

H2O: 1 g/10 mL, clear, colorless

application(s)

pharmaceutical (small molecule)

SMILES string

C[C@@H](O)[C@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

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General description

L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.

Application

L-Threonine has been used for the following :
  • To study the effect of heat on homoserine kinase activity
  • In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells
  • As a substrate to determine the L-threonine dehydrogenase activity
  • To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine

Biochem/physiol Actions

L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

2520072:
T8441-25G:
T8441-BULK:
T8441-100G:
2550088:
T8441-10MG:
T8441-1KG:
T8441-25KG:
T8441-10G:
T8441-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK1971
SLCH6632
SLCF7564
SLCD1572
SLBZ7810

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