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Merck

TOP1MT

topoisomerase (DNA) I, mitochondrial

동의어:
:
UniProtKB ID:
Clone ID:
  • Human(116447) Summary: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(72960) DNA topoisomerase 1, mitochondrial
  • Rat(300029) topoisomerase (DNA) I, mitochondrial
  • Zebrafish(415098) mitochondrial topoisomerase I
  • chicken(408025) topoisomerase (DNA) I, mitochondrial
  • cow(618382) topoisomerase (DNA) I, mitochondrial
  • sheep(101114532) topoisomerase (DNA) I, mitochondrial
  • naked mole-rat(101726319) topoisomerase (DNA) I, mitochondrial
  • domestic guinea pig(100728586) topoisomerase (DNA) I, mitochondrial

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-TOP1MT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-TOP1MT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

제품 번호
설명
Topotecan hydrochloride hydrate, ≥98% (HPLC and enzymatic),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human TOP1MT,
human
MISSION® esiRNA, targeting human TOP1MT (2),
human