TNFRSF18
tumor necrosis factor receptor superfamily, member 18
Synonyms:
AITR, CD357, GITR, GITR-D
Species:
Human TNFRSF18 (8784), Mouse Tnfrsf18 (21936), Rat Tnfrsf18 (500598), Zebrafish tnfrsf18 (571217), domestic cat TNFRSF18 (101083251), dog TNFRSF18 (606971), chicken TNFRSF18 (419424), naked mole-rat Tnfrsf18 (101715065), domestic guinea pig Tnfrsf18 (100715459), cow TNFRSF18 (516256)
UniProtKB ID:
Gene ID:
- Human(8784) Summary: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
- Mouse(21936) tumor necrosis factor receptor superfamily, member 18
- Rat(500598) tumor necrosis factor receptor superfamily, member 18
- Zebrafish(571217) tumor necrosis factor receptor superfamily, member 18
- domestic cat(101083251) tumor necrosis factor receptor superfamily, member 18
- dog(606971) tumor necrosis factor receptor superfamily, member 18
- chicken(419424) tumor necrosis factor receptor superfamily, member 18
- naked mole-rat(101715065) tumor necrosis factor receptor superfamily, member 18
- domestic guinea pig(100715459) tumor necrosis factor receptor superfamily, member 18
- cow(516256) tumor necrosis factor receptor superfamily, member 18
- sheep(101108672) tumor necrosis factor receptor superfamily, member 18
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TNFRSF18 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7787, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-TNFRSF18 (soluble form) Antibody, clone T10P2H9*B9, clone T10P2H9*B9, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-hGITR Antibody, clone 108-17, clone 108-17, from mouse,
Species Reactivity
human, mouse, rat
Application
western blot