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Merck

TNFRSF10A

tumor necrosis factor receptor superfamily, member 10a

Synonyms:
APO2, CD261, DR4, TRAILR-1, TRAILR1
Species:
Human TNFRSF10A (8797), cow TNFRSF10A (781763), domestic guinea pig Tnfrsf10a (101787877)
UniProtKB ID:
O00220, A8K5I4, Q53Y72, Q96E62
Gene ID:
  • Human(8797) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
  • cow(781763) tumor necrosis factor receptor superfamily, member 10a
  • domestic guinea pig(101787877) tumor necrosis factor receptor superfamily, member 10a

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
ZRB3159
Anti-CD261/DR4 Antibody, clone 1B7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
AB16955
Anti-DR4 Antibody, CT, Chemicon®, from rabbit,
Species Reactivity
human
Application
western blot
SAB4700830
Monoclonal Anti-CD261 antibody produced in mouse, clone DR-4-02,
Species Reactivity
human
Application
flow cytometry
SAB4701084
Monoclonal Anti-CD261-APC antibody produced in mouse, clone DR-4-02,
Species Reactivity
Application
flow cytometry
HPA050958
Anti-TNFRSF10A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

Proteins

Product Number
Description
Species
SRP3164
sTRAIL Receptor-1 (DR4) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
EHU008861
MISSION® esiRNA, targeting human TNFRSF10A,
Species
human