RRM1
ribonucleotide reductase M1
Synonyms:
R1, RIR1, RR1
Species:
Human RRM1 (6240), Mouse Rrm1 (20133), Rat Rrm1 (685579), Zebrafish rrm1 (30740), chicken RRM1 (419081), domestic cat RRM1 (101097343), Horse RRM1 (100053126), dog RRM1 (476823), Domestic Rabbit RRM1 (100345823), naked mole-rat Rrm1 (101708047) ...More
UniProtKB ID:
Gene ID:
- Human(6240) Summary: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq, Jul 2008]
- Mouse(20133) ribonucleotide reductase M1
- Rat(685579) ribonucleotide reductase M1
- Zebrafish(30740) ribonucleotide reductase M1 polypeptide
- chicken(419081) ribonucleotide reductase M1
- domestic cat(101097343) ribonucleotide reductase M1
- Horse(100053126) ribonucleotide reductase M1
- dog(476823) ribonucleotide reductase M1
- Domestic Rabbit(100345823) ribonucleotide reductase M1
- naked mole-rat(101708047) ribonucleotide reductase M1
- domestic guinea pig(100728488) ribonucleotide reductase M1
- cow(505537) ribonucleotide reductase M1
- sheep(101116171) ribonucleotide reductase M1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RRM1 Antibody, clone 4P4U1, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-RRM1 Antibody, clone 1E20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species