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PTPRK

protein tyrosine phosphatase, receptor type, K

Synonyms:
R-PTP-kappa
Species:
UniProtKB ID:
Gene ID:
  • Human(5796) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
  • Mouse(19272) protein tyrosine phosphatase, receptor type, K
  • Rat(360302) protein tyrosine phosphatase, receptor type, K
  • Zebrafish(555348) protein tyrosine phosphatase, receptor type, K
  • Horse(100073063) protein tyrosine phosphatase, receptor type, K
  • domestic cat(101092366) protein tyrosine phosphatase, receptor type, K
  • dog(476290) protein tyrosine phosphatase, receptor type, K
  • chicken(421711) protein tyrosine phosphatase, receptor type, K
  • cow(509657) protein tyrosine phosphatase, receptor type, K
  • sheep(101116916) protein tyrosine phosphatase, receptor type, K
  • Domestic Rabbit(100339990) protein tyrosine phosphatase, receptor type, K
  • naked mole-rat(101723444) protein tyrosine phosphatase, receptor type, K
  • domestic guinea pig(100730543) protein tyrosine phosphatase, receptor type, K

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PTPRK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-PTPRK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-PTPRK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PTPRK,
Species
human