PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
Synonyms:
C6, HSPC, RC6-1, XAPC7
Species:
Human PSMA7 (5688), Mouse Psma7 (26444), Rat Psma7 (29674), chicken PSMA7 (395318), dog PSMA7 (404305), domestic cat PSMA7 (101084949), cow PSMA7 (505050), sheep PSMA7 (101121959), naked mole-rat Psma7 (101697423), domestic guinea pig Psma7 (100713525)
UniProtKB ID:
Gene ID:
- Human(5688) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9. [provided by RefSeq, Jul 2012]
- Mouse(26444) proteasome (prosome, macropain) subunit, alpha type 7
- Rat(29674) proteasome (prosome, macropain) subunit, alpha type 7
- chicken(395318) proteasome (prosome, macropain) subunit, alpha type, 7
- dog(404305) proteasome (prosome, macropain) subunit, alpha type, 7
- domestic cat(101084949) proteasome (prosome, macropain) subunit, alpha type, 7
- cow(505050) proteasome (prosome, macropain) subunit, alpha type, 7
- sheep(101121959) proteasome (prosome, macropain) subunit, alpha type, 7
- naked mole-rat(101697423) proteasome (prosome, macropain) subunit, alpha type, 7
- domestic guinea pig(100713525) proteasome (prosome, macropain) subunit, alpha type, 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PSMA7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-PSMA7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry