PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
Synonyms:
PSC5, ZETA
Species:
Human PSMA5 (5686), Mouse Psma5 (26442), Rat Psma5 (29672), cow PSMA5 (510155), sheep PSMA5 (101104946), naked mole-rat Psma5 (101699124), domestic guinea pig Psma5 (100730312), Zebrafish psma5 (403011), chicken PSMA5 (426937), domestic cat PSMA5 (101098808)
UniProtKB ID:
Gene ID:
- Human(5686) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
- Mouse(26442) proteasome (prosome, macropain) subunit, alpha type 5
- Rat(29672) proteasome (prosome, macropain) subunit, alpha type 5
- cow(510155) proteasome (prosome, macropain) subunit, alpha type, 5
- sheep(101104946) proteasome (prosome, macropain) subunit, alpha type, 5
- naked mole-rat(101699124) proteasome (prosome, macropain) subunit, alpha type, 5
- domestic guinea pig(100730312) proteasome (prosome, macropain) subunit, alpha type, 5
- Zebrafish(403011) proteasome (prosome, macropain) subunit, alpha type,5
- chicken(426937) proteasome (prosome, macropain) subunit, alpha type, 5
- domestic cat(101098808) proteasome (prosome, macropain) subunit, alpha type, 5
- dog(490123) proteasome (prosome, macropain) subunit, alpha type, 5
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