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Merck

PPIA

peptidylprolyl isomerase A (cyclophilin A)

Synonyms:
CYPA, CYPH
Species:
Human PPIA (5478), Mouse Ppia (268373), Rat Ppia (25518), chicken PPIA (776282), domestic cat PPIA (493966), dog PPIA (608151), cow PPIA (786614), cow PPIA (281418), sheep PPIA (443258), Goat PPIA (100860961)
UniProtKB ID:
P62937, A8K220, P05092, Q3KQW3, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9
Gene ID:
  • Human(5478) Summary: This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(268373) peptidylprolyl isomerase A
  • Rat(25518) peptidylprolyl isomerase A (cyclophilin A)
  • chicken(776282) peptidylprolyl isomerase A (cyclophilin A)
  • domestic cat(493966) peptidylprolyl isomerase A (cyclophilin A)
  • dog(608151) peptidylprolyl isomerase A (cyclophilin A)
  • cow(786614) TRIM5/cyclophilin A fusion protein-like
  • cow(281418) peptidylprolyl isomerase A (cyclophilin A)
  • sheep(443258) peptidylprolyl isomerase A (cyclophilin A)
  • Goat(100860961) peptidylprolyl isomerase A (cyclophilin A)
  • Domestic Rabbit(100008724) peptidylprolyl isomerase A (cyclophilin A)

Custom & Knockdown Gene Products

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
30024
Cyclosporin A, 97.0-101.5% (on dried basis),
Species
human
C1832
Cyclosporin A, BioReagent, from Tolypocladium inflatum, for molecular biology, ≥95%,
Species
human
C3662
Cyclosporin A, from Tolypocladium inflatum, ≥95% (HPLC), solid,
Species
human

Proteins

Product Number
Description
Species
C3805
Cyclophilin A human, ≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
EMU161851
MISSION® esiRNA, targeting mouse Ppia,
Species
mouse
EHU107101
MISSION® esiRNA, targeting human PPIA,
Species
human