POLH
polymerase (DNA directed), eta
Synonyms:
RAD30, RAD30A, XP-V, XPV
Species:
Human POLH (5429), Mouse Polh (80905), Rat Polh (316235), Thale Cress POLH (834503), Zebrafish polh (678520), dog POLH (474915), Horse POLH (100067518), domestic cat POLH (101088666), chicken POLH (395102), naked mole-rat Polh (101708877) ...More
UniProtKB ID:
Gene ID:
- Human(5429) Summary: This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq, Jul 2008]
- Mouse(80905) polymerase (DNA directed), eta (RAD 30 related)
- Rat(316235) polymerase (DNA directed), eta
- Thale Cress(834503) Y-family DNA polymerase H
- Zebrafish(678520) polymerase (DNA directed), eta
- dog(474915) polymerase (DNA directed), eta
- Horse(100067518) polymerase (DNA directed), eta
- domestic cat(101088666) polymerase (DNA directed), eta
- chicken(395102) polymerase (DNA directed), eta
- naked mole-rat(101708877) polymerase (DNA directed), eta
- Domestic Rabbit(100357494) polymerase (DNA directed), eta
- domestic guinea pig(100732400) polymerase (DNA directed), eta
- cow(513606) polymerase (DNA directed), eta
- sheep(101115320) polymerase (DNA directed), eta
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-POLH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-POLH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-POLH antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-POLH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot