PCSK9
proprotein convertase subtilisin/kexin type 9
Synonyms:
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9
Species:
Human PCSK9 (255738), Mouse Pcsk9 (100102), Rat Pcsk9 (298296), Zebrafish pcsk9 (100150316), chicken PCSK9 (424664), domestic guinea pig Pcsk9 (100731533), naked mole-rat Pcsk9 (101700911)
UniProtKB ID:
Gene ID:
- Human(255738) Summary: This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq, Jul 2008]
- Mouse(100102) proprotein convertase subtilisin/kexin type 9
- Rat(298296) proprotein convertase subtilisin/kexin type 9
- Zebrafish(100150316) proprotein convertase subtilisin/kexin type 9
- chicken(424664) proprotein convertase subtilisin/kexin type 9
- domestic guinea pig(100731533) proprotein convertase subtilisin/kexin type 9
- naked mole-rat(101700911) proprotein convertase subtilisin/kexin type 9
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PCSK9 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunocytochemistry
western blot
western blot
[KD Validated]Anti-PCSK9 Antibody, clone 9L4U5, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot