PCDHA6
protocadherin alpha 6
Synonyms:
CNR2, CNRN2, CNRS2, CRNR2, PCDH-ALPHA6
Species:
Human PCDHA6 (56142), Mouse Pcdha6 (12937), Rat Pcdha6 (393088), chicken PCDHA6 (497216), domestic cat PCDHA6 (101099699), dog PCDHA6 (607224), cow PCDHA6 (616024)
UniProtKB ID:
Gene ID:
- Human(56142) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- Mouse(12937) protocadherin alpha 6
- Rat(393088) protocadherin alpha 6
- chicken(497216) protocadherin alpha 6
- domestic cat(101099699) protocadherin alpha 6
- dog(607224) protocadherin alpha 6
- cow(616024) protocadherin alpha 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PCDHA6 antibody produced in mouse, clone 1A3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-PCDHA6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-PCDHA6, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-PCDHA6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PCDHA6 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot