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MilliporeSigma

NCOR1

nuclear receptor corepressor 1

Synonyms:
N-CoR, N-CoR1, TRAC1, hN-CoR
Species:
Human NCOR1 (9611), Mouse Ncor1 (20185), Rat Ncor1 (54299), sheep NCOR1 (101117774), naked mole-rat Ncor1 (101715929), domestic guinea pig Ncor1 (100722145), Zebrafish ncor1 (393246), cow NCOR1 (507663), Horse NCOR1 (100063285), dog NCOR1 (479515)
UniProtKB ID:
O75376, B3DLF8, E9PGV6, Q86YY0, Q9UPV5, Q9UQ18
Gene ID:
  • Human(9611) Summary: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
  • Mouse(20185) nuclear receptor co-repressor 1
  • Rat(54299) nuclear receptor co-repressor 1
  • sheep(101117774) nuclear receptor corepressor 1
  • naked mole-rat(101715929) nuclear receptor corepressor 1
  • domestic guinea pig(100722145) nuclear receptor corepressor 1
  • Zebrafish(393246) nuclear receptor co-repressor 1
  • cow(507663) nuclear receptor corepressor 1
  • Horse(100063285) nuclear receptor corepressor 1
  • dog(479515) nuclear receptor corepressor 1
  • chicken(417598) nuclear receptor corepressor 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
ABE251
Anti-N-CoR Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
western blot
AV32479
Anti-NCOR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse
Application
immunohistochemistry
western blot
HPA050288
Anti-NCOR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
HPA051168
Anti-NCOR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
HPA043246
Anti-NCOR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

Proteins

Product Number
Description
Species
SRP2073
N-CoR human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU065611
MISSION® esiRNA, targeting human NCOR1,
Species
human