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MYD88

myeloid differentiation primary response 88

Synonyms:
MYD88D
Species:
UniProtKB ID:
Gene ID:
  • Human(4615) Summary: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
  • Mouse(17874) myeloid differentiation primary response gene 88
  • Rat(301059) myeloid differentiation primary response 88
  • Zebrafish(403145) myeloid differentiation primary response gene (88)
  • fruit fly(35956) CG2078 gene product from transcript CG2078-RB
  • domestic cat(101087092) myeloid differentiation primary response gene (88)
  • cow(444881) myeloid differentiation primary response gene (88)
  • dog(477024) myeloid differentiation primary response gene (88)
  • chicken(420420) myeloid differentiation primary response gene (88)
  • naked mole-rat(101712637) myeloid differentiation primary response 88
  • domestic guinea pig(100733381) myeloid differentiation primary response 88
  • sheep(678682) myeloid differentiation primary response gene (88)

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MyD88 antibody produced in mouse, clone 2E9C2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-MYD88, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-MYD88 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, goat, horse, human, pig, rabbit, rat, sheep
Application
western blot
Anti-MYD88 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, chimpanzee, human, mouse, rat
Application
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-MYD88 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Myd88,
Species
mouse
MISSION® esiRNA, targeting human MYD88,
Species
human