MAP3K12
mitogen-activated protein kinase kinase kinase 12
Synonyms:
DLK, MEKK12, MUK, ZPK, ZPKP1
Species:
Human MAP3K12 (7786), Mouse Map3k12 (26404), Rat Map3k12 (25579), Zebrafish map3k12 (404626), chicken MAP3K12 (101669120), cow MAP3K12 (505427), Horse MAP3K12 (100064002), domestic cat MAP3K12 (101087164), dog MAP3K12 (607170), chicken MAP3K12 (101750914) ...More
UniProtKB ID:
Gene ID:
- Human(7786) Summary: This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010]
- Mouse(26404) mitogen-activated protein kinase kinase kinase 12
- Rat(25579) mitogen activated protein kinase kinase kinase 12
- Zebrafish(404626) mitogen-activated protein kinase kinase kinase 12
- chicken(101669120) mitogen-activated protein kinase kinase kinase 12
- cow(505427) mitogen-activated protein kinase kinase kinase 12
- Horse(100064002) mitogen-activated protein kinase kinase kinase 12
- domestic cat(101087164) mitogen-activated protein kinase kinase kinase 12
- dog(607170) mitogen-activated protein kinase kinase kinase 12
- chicken(101750914) mitogen-activated protein kinase kinase kinase 12
- Domestic Rabbit(100358158) mitogen-activated protein kinase kinase kinase 12
- naked mole-rat(101702332) mitogen-activated protein kinase kinase kinase 12
- domestic guinea pig(100731317) mitogen-activated protein kinase kinase kinase 12
- sheep(101102889) mitogen-activated protein kinase kinase kinase 12
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Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-MAP3K12 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-MAP3K12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MAP3K12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Proteins
Product Number
Description
Species
DLK, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human