KRIT1
KRIT1, ankyrin repeat containing
Synonyms:
CAM, CCM1
Species:
Human KRIT1 (889), Mouse Krit1 (79264), Rat Krit1 (362317), Zebrafish krit1 (321836), cow KRIT1 (407996), Horse KRIT1 (100050998), domestic cat KRIT1 (101083757), dog KRIT1 (482299), chicken KRIT1 (420549), domestic guinea pig Krit1 (100731041) ...More
UniProtKB ID:
Gene ID:
- Human(889) Summary: This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(79264) KRIT1, ankyrin repeat containing
- Rat(362317) KRIT1, ankyrin repeat containing
- Zebrafish(321836) KRIT1, ankyrin repeat containing
- cow(407996) KRIT1, ankyrin repeat containing
- Horse(100050998) KRIT1, ankyrin repeat containing
- domestic cat(101083757) KRIT1, ankyrin repeat containing
- dog(482299) KRIT1, ankyrin repeat containing
- chicken(420549) KRIT1, ankyrin repeat containing
- domestic guinea pig(100731041) KRIT1, ankyrin repeat containing
- naked mole-rat(101725749) KRIT1, ankyrin repeat containing
- sheep(101110497) KRIT1, ankyrin repeat containing
- Domestic Rabbit(100344408) KRIT1, ankyrin repeat containing
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-KRIT1 antibody produced in mouse, clone 2C7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-KRIT1, (C-terminal) antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-KRIT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-KRIT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry