G6PC
glucose-6-phosphatase, catalytic subunit
Synonyms:
G6PC1, G6PT, GSD1, GSD1a
Species:
Human G6PC (2538), Mouse G6pc (14377), Rat G6pc (25634), domestic cat G6PC (723970), dog G6PC (403492), cow G6PC (538710), domestic guinea pig G6pc (100720420), naked mole-rat G6pc (101708598)
UniProtKB ID:
Gene ID:
- Human(2538) Summary: Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]
- Mouse(14377) glucose-6-phosphatase, catalytic
- Rat(25634) glucose-6-phosphatase, catalytic subunit
- domestic cat(723970) glucose-6-phosphatase, catalytic subunit
- dog(403492) glucose-6-phosphatase, catalytic subunit
- cow(538710) glucose-6-phosphatase, catalytic subunit
- domestic guinea pig(100720420) glucose-6-phosphatase, catalytic subunit
- naked mole-rat(101708598) glucose-6-phosphatase, catalytic subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti--G6PC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5818, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti--G6PC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5817, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-G6PC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-G6PC, affinity isolated antibody,
Species Reactivity
dog, human, pig, sheep
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species