G6PC
glucose-6-phosphatase, catalytic subunit
Synonyms:
G6PC1, G6PT, GSD1, GSD1a
Species:
Human G6PC (2538), Mouse G6pc (14377), Rat G6pc (25634), domestic cat G6PC (723970), dog G6PC (403492), cow G6PC (538710), domestic guinea pig G6pc (100720420), naked mole-rat G6pc (101708598)
UniProtKB ID:
Gene ID:
- Human(2538) Summary: Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]
- Mouse(14377) glucose-6-phosphatase, catalytic
- Rat(25634) glucose-6-phosphatase, catalytic subunit
- domestic cat(723970) glucose-6-phosphatase, catalytic subunit
- dog(403492) glucose-6-phosphatase, catalytic subunit
- cow(538710) glucose-6-phosphatase, catalytic subunit
- domestic guinea pig(100720420) glucose-6-phosphatase, catalytic subunit
- naked mole-rat(101708598) glucose-6-phosphatase, catalytic subunit
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Inhibitor
Product Number
Description
Species