์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck

DMP1

dentin matrix acidic phosphoprotein 1

๋™์˜์–ด:
ARHP, ARHR, DMP-1
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UniProtKB ID:
Clone ID:
  • Human(1758) Summary: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13406) dentin matrix protein 1
  • Rat(25312) dentin matrix acidic phosphoprotein 1
  • Thale Cress(821706) DUF679 domain membrane protein 1
  • chicken(404539) dentin matrix acidic phosphoprotein 1
  • dog(487849) dentin matrix acidic phosphoprotein 1
  • domestic cat(101095652) dentin matrix acidic phosphoprotein 1
  • cow(281118) dentin matrix acidic phosphoprotein 1
  • sheep(101123558) dentin matrix acidic phosphoprotein 1
  • sheep(100861441) dentin matrix acidic phosphoprotein 1
  • domestic guinea pig(100732102) dentin matrix acidic phosphoprotein 1
  • naked mole-rat(101725040) dentin matrix acidic phosphoprotein 1

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ELISA

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Human DMP1 / Dentin Matrix Acidic Phosphoprotein 1 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
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human

Antibodies

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Anti-DMP1 antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
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human
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immunohistochemistry
Anti-DMP1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
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human
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ELISA
western blot
Anti-DMP-1 (CT) Antibody, clone 8G10.3, clone 8G10.3, from mouse,
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human, mouse, rat
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dot blot
immunohistochemistry

esiRNA

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MISSIONยฎ esiRNA, targeting human DMP1,
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human