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DAND5

DAN domain family member 5, BMP antagonist

Synonyms:
CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, SP1
Species:
UniProtKB ID:
Gene ID:
  • Human(199699) Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
  • Mouse(23863) DAN domain family, member 5
  • Rat(685719) DAN domain family, member 5
  • domestic guinea pig(100727384) DAN domain family member 5, BMP antagonist
  • naked mole-rat(101721262) DAN domain family member 5, BMP antagonist
  • Zebrafish(791454) DAN domain family, member 5
  • dog(484921) DAN domain family, member 5

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ELISA

Product Number
Description
Species
Human DAND5 / DAN Domain Family Member 5 ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-DAND5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-DAND5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Dand5,
Species
mouse