COX11
cytochrome c oxidase assembly homolog 11 (yeast)
Synonyms:
COX11P
Species:
Human COX11 (1353), Mouse Cox11 (69802), Rat Cox11 (690300), Zebrafish cox11 (100005158), chicken COX11 (770638), cow COX11 (510509), dog COX11 (609555)
UniProtKB ID:
Gene ID:
- Human(1353) Summary: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009]
- Mouse(69802) cytochrome c oxidase assembly protein 11
- Rat(690300) cytochrome c oxidase assembly homolog 11 (yeast)
- Zebrafish(100005158) COX11 cytochrome c oxidase assembly homolog (yeast)
- chicken(770638) COX11 cytochrome c oxidase assembly homolog (yeast)
- cow(510509) COX11 cytochrome c oxidase assembly homolog (yeast)
- dog(609555) COX11 cytochrome c oxidase assembly homolog (yeast)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-COX11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species