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Merck

CAMK2B

calcium/calmodulin-dependent protein kinase II beta

Synonyms:
CAM2, CAMK2, CAMKB
Species:
Human CAMK2B (816), Mouse Camk2b (12323), Rat Camk2b (24245), chicken CAMK2B (374174), dog CAMK2B (608846), domestic cat CAMK2B (101098615), cow CAMK2B (525416), Horse CAMK2B (100146368), domestic guinea pig Camk2b (100717077), naked mole-rat Camk2b (101718749)
UniProtKB ID:
Q13554, A4D2K0, A4D2K1, A4D2K2, A4D2K3, A4D2K4, A4D2K5, A4D2K6
Gene ID:
  • Human(816) Summary: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12323) calcium/calmodulin-dependent protein kinase II, beta
  • Rat(24245) calcium/calmodulin-dependent protein kinase II beta
  • chicken(374174) calcium/calmodulin-dependent protein kinase II beta
  • dog(608846) calcium/calmodulin-dependent protein kinase II beta
  • domestic cat(101098615) calcium/calmodulin-dependent protein kinase II beta
  • cow(525416) calcium/calmodulin-dependent protein kinase II beta
  • Horse(100146368) calcium/calmodulin-dependent protein kinase II beta
  • domestic guinea pig(100717077) calcium/calmodulin-dependent protein kinase II beta
  • naked mole-rat(101718749) calcium/calmodulin-dependent protein kinase II beta
  • sheep(101118870) calcium/calmodulin-dependent protein kinase II beta

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Small Molecule - Antagonist

Product Number
Description
Species
A3281
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB5701970
Anti-CaMKII Antibody, clone 7L9F0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
ZRB2954
Anti-CaM Kinase II β Antibody, clone 1F13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
ABS2107M
Anti-phospho-CaMKII beta (Ser331), from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunocytochemistry
western blot

Proteins

Product Number
Description
Species
C4926
Calmodulin-dependent Protein Kinase II fragment 290-309, ≥97% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
EHU059191
MISSION® esiRNA, targeting human CAMK2B,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
A4308
Autocamtide 2-related inhibitory peptide, ≥97% (HPLC), lyophilized powder,
Species
mouse, rat, human