BRAF
v-raf murine sarcoma viral oncogene homolog B
Synonyms:
B-RAF1, BRAF1, NS7, RAFB1
Species:
Human BRAF (673), Mouse Braf (109880), Rat Braf (114486), Zebrafish braf (403065), cow BRAF (536051), Horse BRAF (100065760), domestic cat BRAF (101092346), dog BRAF (475526), chicken BRAF (396239), naked mole-rat Braf (101702762) ...More
UniProtKB ID:
Gene ID:
- Human(673) Summary: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109880) Braf transforming gene
- Rat(114486) v-raf murine sarcoma viral oncogene homolog B
- Zebrafish(403065) v-raf murine sarcoma viral oncogene homolog B1
- cow(536051) v-raf murine sarcoma viral oncogene homolog B
- Horse(100065760) v-raf murine sarcoma viral oncogene homolog B1
- domestic cat(101092346) v-raf murine sarcoma viral oncogene homolog B1
- dog(475526) v-raf murine sarcoma viral oncogene homolog B1
- chicken(396239) v-raf murine sarcoma viral oncogene homolog B1
- naked mole-rat(101702762) v-raf murine sarcoma viral oncogene homolog B1
- domestic guinea pig(100717765) v-raf murine sarcoma viral oncogene homolog B1
- sheep(101107438) v-raf murine sarcoma viral oncogene homolog B1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-BRAF (V600E) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-Phospho-BRAF-S445 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot
Anti-BRAF (V600E) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Phospho-B-Raf-T401 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-phospho-B-Raf (pThr753) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Cell Lines
Product Number
Description
Species
Proteins
Product Number
Description
Species
BRAF (416-766), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human