BMPR1B
bone morphogenetic protein receptor, type IB
Synonyms:
ALK-6, ALK6, CDw293
Species:
Human BMPR1B (658), Mouse Bmpr1b (12167), Rat Bmpr1b (310914), chicken BMPR1B (396030), dog BMPR1B (478484), cow BMPR1B (407128), domestic cat BMPR1B (101082489), domestic guinea pig Bmpr1b (100732675), naked mole-rat Bmpr1b (101710196), sheep BMPR1B (443454)
UniProtKB ID:
Gene ID:
- Human(658) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
- Mouse(12167) bone morphogenetic protein receptor, type 1B
- Rat(310914) bone morphogenetic protein receptor, type IB
- chicken(396030) bone morphogenetic protein receptor, type IB
- dog(478484) bone morphogenetic protein receptor, type IB
- cow(407128) bone morphogenetic protein receptor, type IB
- domestic cat(101082489) bone morphogenetic protein receptor, type IB
- domestic guinea pig(100732675) bone morphogenetic protein receptor, type IB
- naked mole-rat(101710196) bone morphogenetic protein receptor, type IB
- sheep(443454) bone morphogenetic protein receptor, type IB
- Domestic Rabbit(100351275) bone morphogenetic protein receptor, type IB
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-BMPR1B antibody produced in mouse, clone 2F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-BMPR1B antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot