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MilliporeSigma

BAK1

BCL2-antagonist/killer 1

Synonyms:
BAK, BAK-LIKE, BCL2L7, CDN1
Species:
Human BAK1 (578), Mouse Bak1 (12018), Rat Bak1 (116502), domestic guinea pig Bak1 (100734553), Thale Cress BAK1 (829480), cow BAK1 (514090), domestic cat BAK1 (768278), domestic cat BAK1 (101093435), dog BAK1 (481744), chicken BAK1 (419912)
UniProtKB ID:
Q16611, Q6I9T6, Q92533
Gene ID:
  • Human(578) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
  • Mouse(12018) BCL2-antagonist/killer 1
  • Rat(116502) BCL2-antagonist/killer 1
  • domestic guinea pig(100734553) BCL2-antagonist/killer 1
  • Thale Cress(829480) Leu-rich receptor Serine/threonine protein kinase BAK1
  • cow(514090) BCL2-antagonist/killer 1
  • domestic cat(768278) BCL2-antagonist/killer 1
  • domestic cat(101093435) BCL2-antagonist/killer 1
  • dog(481744) BCL2-antagonist/killer 1
  • chicken(419912) BCL2-antagonist/killer 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
B5897
Anti-Bak antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
microarray
western blot
SAB4502532
Anti-BAK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
SAB1305656
ANTI-BAK (BH3 DOMAIN SPECIFIC) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
06-536
Anti-Bak Antibody, NT, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
ZRB1453
Anti-Bak Antibody, clone 2D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU113511
MISSION® esiRNA, targeting human BAK1,
Species
human