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ATP1B3

ATPase, Na+/K+ transporting, beta 3 polypeptide

Synonyms:
ATPB-3, CD298
Species:
UniProtKB ID:
Gene ID:
  • Human(483) Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]
  • Mouse(11933) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Rat(25390) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • chicken(396549) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • dog(477098) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • domestic cat(101097586) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Horse(100062895) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • cow(532844) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • Domestic Rabbit(100008788) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • naked mole-rat(101697891) ATPase, Na+/K+ transporting, beta 3 polypeptide
  • domestic guinea pig(100135484) ATPase, Na+/K+ transporting, beta 3 polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ATP1B3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Digitoxin, British Pharmacopoeia (BP) Reference Standard,
Species
human
Digoxin for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Species
human
Digitoxin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Digitoxin, phyproof® Reference Substance,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ATP1B3,
Species
human
MISSION® esiRNA, targeting mouse Atp1b3,
Species
mouse