Skip to Content
MilliporeSigma

ACTL6B

actin-like 6B

Synonyms:
ACTL6, BAF53B
Species:
UniProtKB ID:
Gene ID:
  • Human(51412) Summary: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. [provided by RefSeq, Jul 2008]
  • Mouse(83766) actin-like 6B
  • Rat(288563) actin-like 6B
  • Zebrafish(553775) actin-like 6B
  • dog(608417) actin-like 6B
  • cow(504476) actin-like 6B
  • domestic cat(101093067) actin-like 6B
  • sheep(101103114) actin-like 6B
  • naked mole-rat(101712102) actin-like 6B
  • domestic guinea pig(100719784) actin-like 6B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ACTL6B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACTL6B,
Species
human