Skip to Content
Merck
HomeProductsProtein BiologyProteins & EnzymesGlycobiology Profiling Tools

Glycobiology Profiling Tools

N-glycan structure with a wrench attached. Glycobiology profiling tools to support glycoprotein analysis, prep, modification and other glycobiology workflow needs.

Explore our latest innovations in glycobiology and glycoproteomics research: Mucinase StcE, Mucinase SmE, and a powerful Mucin Degradation Enzyme. These cutting-edge enzymes efficiently break down complex mucin structures, enabling deeper insights into mucin biology, host-pathogen interactions, and mucosal barrier studies. Additionally, they support advanced glycoproteomics workflows by improving access to mucin-associated glycopeptides, enhancing glycan profiling, and enabling more precise characterization of glycosylation patterns. Whether you're investigating glycoprotein modifications, studying disease mechanisms, or developing novel therapeutics, these high-purity enzymes provide reliable, reproducible performance to accelerate your discoveries.

Products

Compare
Product Number
Product Name
Product Description
Pricing

Glycobiology Profiling Categories

To accommodate your glycobiology workflow needs, we offer a wide range of products for functional and structural analysis of glycans, including glycoprocessing and glycosylation enzymes, glycan labels, lectins, capture resins, standards, glycoproteins, and free oligosaccharides. This includes offerings of carbohydrate-recognizing proteins such as lectins and galectins, carbohydrate-active enzymes like glycosidases (exoglycosidases, endoglycosidases), and glycosyltransferases. Additionally, our GlycoProfile™ kits are a curated product line that have been developed to simplify common workflows including release and labeling of N-linked and O-linked glycans.

The glycobiology profiling tools we offer can be broken into these 4 categories:

Capture step of glycobiology workflow where enzyme is attaching to glycan structures.

CAPTURE

Release step of glycobiology workflow with a depiction of N-glycans and O-glycan structures.

RELEASE

Modify step of glycobiology workflow with a depiction of modifying glycan structures. Erlenmeyer flask in the middle of a circular process workflow with glycans linked to the left and glycans broken apart on the right.

MODIFY

Analyze step of glycobiology workflow with a depiction of N-linked glycan structures that are tagged with labels for analyzing.

ANALYZE

Related Resources

Page 1 of 4
Related Product Categories
Protein Mass Spectrometry
To meet your mass spectrometry needs, explore our comprehensive offering of kits, tagging reagents, calibrants, and MS standards.
Tissue Dissociation
Discover efficient cell detachment: reliable enzymes - trypsin, collagenase, papain, nucleases, hyaluronidase, elastase, protease XIV.
Nucleases (DNases and RNases)
Nucleases, including high-purity DNase, RNase, and phosphodiesterase enzymes to support your nucleic acid digestion application needs.
Detection Substrates & Enzymes
Substrates and enzymes are crucial in life science research, both as tools and targets in detection systems. Discover enzyme-based protein detection systems for ELISA, immunohistochemistry, western blotting, and many more with our diverse portfolio of detection substrates and enzymes.
Proteases
Protease reagents and resources for endo- and exopeptidase cleavage application needs and resources for your protein cleavage workflow.
Carbohydrates for Biochemical Research
Purchase monosaccharides, disaccharides, polysaccharides & dextrans for your cell culture, metabolomics, glycobiology, microbiome, and nutrition research.
Proteins & Enzymes
Browse protein, enzyme, and small molecule products for cell biology, culture supplementation, and pathway studies.
Related Applications
Glycobiology
Glycobiology studies the structure, biosynthesis, biology, and evolution of carbohydrates, or glycans, and how disorders in these processes play a role in diseases, in order to develop glyocotherapeutics.
Protein Mass Spectrometry
An overview of techniques for protein mass spectrometry used in the identification and quantification of proteins, post-translational modifications, glycan profiling, and protein-protein interactions in drug discovery and proteomics research.
Gel Electrophoresis
Protein gel electrophoresis is used to separate proteins for purification, characterization, and detection. Methods such as native PAGE, SDS-PAGE, 2D PAGE, and isoelectric focusing (IEF) are used in preparation for downstream applications including Western blotting, mass spectrometry, and proteomic analysis.
Western Blotting
An overview of the principles and applications of Western blotting for protein detection. Includes links to detailed protocols, videos, and other resources for protein extraction, gel electrophoresis, transfer to PVDF or nitrocellulose membranes, and chemiluminescent, colorimetric, and fluorescent detection methods.
Protein Labeling & Modification
Protein labeling applications using enzyme-protein labeling, fluorescent protein labeling, and targeted protein degradation technologies.
Protein Expression
Protein expression technologies for various expression systems supporting research, therapeutics, and vaccine production.
Protein Purification
Protein purification techniques, reagents, and protocols for purifying recombinant proteins using methods including, ion-exchange, size-exclusion, and protein affinity chromatography.
Protein Structural Analysis
Protein structure provides valuable information that can be used to infer protein function. The study of protein structure and mapping of protein interactions, expression levels, and location enables the identification of disease biomarkers and potential drug targets for therapeutic treatment.
Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?