- RING finger protein 113A regulates C-X-C chemokine receptor type 4 stability and signaling.
RING finger protein 113A regulates C-X-C chemokine receptor type 4 stability and signaling.
American journal of physiology. Cell physiology (2017-10-06)
Travis Lear, Sarah R Dunn, Alison C McKelvey, Aazrin Mir, John Evankovich, Bill B Chen, Yuan Liu
PMID28978524
ABSTRACT
As an α-chemokine receptor specific for stromal-derived-factor-1 (SDF-1, also called CXCL12), C-X-C chemokine receptor type 4 (CXCR4) plays a vital role in chemotactically attracting lymphocytes during inflammation. CXCR4 also regulates HIV infection due to its role as one of the chemokine coreceptors for HIV entry into CD4