biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
human
concentration
0.78 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer257)
Gene Information
human ... MAP2K4(6416)
General description
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Immunogen
A synthetic phosphorylated peptide around S257 of human MAP2K4 (NP_003001.1).
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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