SAB3500380
Anti-LXR-B antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-LXRB, Anti-Liver X receptor B, Anti-NR1H2, Anti-Nuclear receptor subfamily 1 group H member 2
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
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General description
Liver X receptor β (LXRβ ) is a member of LXRs that belong to the nuclear receptor superfamily. It possesses a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The protein is expressed in many tissues and the LXRβ gene is localized on human chromosome 19q13.3.
Immunogen
LXR-B antibody was raised against a 14 amino acid peptide from near the amino terminus human LXR-B.
Biochem/physiol Actions
Liver X receptor β (LXRβ) has a role in cell death and cholesterol metabolism. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Linkage
The action of this antibody can be blocked using blocking peptide SBP3500380.
Physical form
Supplied in PBS with 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Find documentation for the products that you have recently purchased in the Document Library.
A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.
Mouzat K
BMC Medical Genetics (2011)
Liver X receptor ? activation induces pyroptosis of human and murine colon cancer cells.
Derangere V
Cell Death and Differentiation (2014)
Liver x receptors in atherosclerosis and inflammation.
Im SS and Osborne TF
Circulation Research (2011)
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