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SAB1406136

Sigma-Aldrich

Anti-MMP13 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

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1 G
SGD 316.00

SGD 316.00

Estimated to ship onApril 17, 2025Details

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1 G
SGD 316.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

SGD 316.00

Estimated to ship onApril 17, 2025Details

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~53.8 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

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manufacturer/tradename

Axygen Inc T-400-L-R-S, Corning

manufacturer/tradename

Axygen Inc T-400-L, Corning

manufacturer/tradename

Axygen Inc T-400-L-R, Corning

manufacturer/tradename

Axygen Inc T-300-L-STK-S, Corning

sterility

sterile

sterility

non-sterile

sterility

-

sterility

sterile

material

clear

material

clear

material

-

material

-

packaging

pkg of 5x960tips/cs

packaging

pkg of 20x1000tips/cs

packaging

pkg of 5x960tips/cs

packaging

pkg of 10x480tips/cs

size

0.5-10 μL

size

0.5-10 μL

size

0.5-10 μL

size

0.5-10 μL

General description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. (provided by RefSeq)

Immunogen

MMP13 (NP_002418, 1 a.a. ~ 471 a.a) full-length human protein.

Sequence
MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC

Physical form

Solution in phosphate buffered saline, pH 7.4

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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    Lot/Batch Number
    08352

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    H Iijima et al.
    Osteoarthritis and cartilage, 22(7), 1036-1043 (2014-05-27)
    This study aimed to investigate subchondral bone changes using micro-computed tomography (micro-CT) and regional differences in articular cartilage degeneration, focusing on changes of cartilage covered by menisci, in the early phase using a destabilization of the medial meniscus (DMM) model.
    K Chen et al.
    International journal of oral and maxillofacial surgery, 43(8), 996-1004 (2014-05-09)
    This study investigated the effects of intra-articular injection of alendronate on the mandibular condyle in ovariectomized rats. Sixty rats were divided into five groups: ovariectomy with vehicle treatment alone, early alendronate treatment at ovariectomy, late alendronate treatment at 4 weeks
    Chuan Ma et al.
    PloS one, 9(9), e107544-e107544 (2014-09-17)
    To examine the possible involvement and regulatory mechanisms of extracellular signal-regulated kinase (ERK) pathway in the temporomandibular joint (TMJ) of rats subjected to chronic sleep deprivation (CSD). Rats were subjected to CSD using the modified multiple platform method (MMPM). The

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