PILRA
paired immunoglobin-like type 2 receptor alpha
Synonyms:
FDF03
Species:
Human PILRA (29992), Mouse Pilra (231805), Rat Pilra (288568), dog PILRA (489841), domestic guinea pig Pilra (100715696), naked mole-rat Pilra (101721193), cow PILRA (100137734), sheep PILRA (101122158)
UniProtKB ID:
Gene ID:
- Human(29992) Summary: Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008]
- Mouse(231805) paired immunoglobin-like type 2 receptor alpha
- Rat(288568) paired immunoglobin-like type 2 receptor alpha
- dog(489841) paired immunoglobin-like type 2 receptor alpha
- domestic guinea pig(100715696) paired immunoglobin-like type 2 receptor alpha
- naked mole-rat(101721193) paired immunoglobin-like type 2 receptor alpha
- cow(100137734) paired immunoglobin-like type 2 receptor alpha
- sheep(101122158) paired immunoglobin-like type 2 receptor alpha
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PILRA antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-PILRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-PILRA antibody produced in mouse, clone 3C2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot