The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells.

The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells.

Nature communications (2016-09-27)

Hye-Jin Boo, Hye-Young Min, Hyun-Ji Jang, Hye Jeong Yun, John Kendal Smith, Quanri Jin, Hyo-Jong Lee, Diane Liu, Hee-Seok Kweon, Carmen Behrens, J Jack Lee, Ignacio I Wistuba, Euni Lee, Waun Ki Hong, Ho-Young Lee

PMID27666821

ABSTRACT

Nicotinic acetylcholine receptors (nAChRs) binding to the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces Ca

MATERIALS

Product Number

Brand

Product Description

EHU091501

Sigma-Aldrich

MISSION^® esiRNA, targeting human RAB27A

T5168

Sigma-Aldrich

Monoclonal Anti-α-Tubulin antibody produced in mouse, ascites fluid, clone B-5-1-2