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WH0008837M1

Sigma-Aldrich

Monoclonal Anti-CFLAR antibody produced in mouse

clone 2F12, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-CASH, Anti-CASP8 and FADD-like apoptosis regulator, Anti-CASP8AP1, Anti-CLARP, Anti-Casper, Anti-FLAME, Anti-FLAME1, Anti-FLIP, Anti-IFLICE, Anti-MRIT, Anti-USURPIN, Anti-cFLIP, Anti-cFLIPL, Anti-cFLIPR, Anti-cFLIPS

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25 MG
SGD 159.00

SGD 159.00


Estimated to ship onApril 17, 2025Details



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25 MG
SGD 159.00

About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

SGD 159.00


Estimated to ship onApril 17, 2025Details


biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2F12, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL

isotype

IgG2aκ

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This Item
SAB1406737HPA019044AV00022
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

rabbit

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

IgG fraction of antiserum

clone

2F12, monoclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

Gene Information

human ... CFLAR(8837)

Gene Information

human ... CFLAR(8837)

Gene Information

human ... CFLAR(8837)

Gene Information

human ... CFLAR(8837)

Immunogen

CFLAR (AAH01602, 178 a.a. ~ 277 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
AGTSYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYE

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Sireesha V Garimella et al.
    Breast cancer research : BCR, 16(2), R41-R41 (2014-04-22)
    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to its receptors, TRAIL-receptor 1 (TRAIL-R1) and TRAIL-receptor 2 (TRAIL-R2), leading to apoptosis by activation of caspase-8 and the downstream executioner caspases, caspase-3 and caspase-7 (caspase-3/7). Triple-negative breast cancer (TNBC) cell lines with

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