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About This Item
Empirical Formula (Hill Notation):
C8H17N3O2 · 2 HCl
CAS Number:
Molecular Weight:
260.16
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.77
biological source
synthetic (organic)
Assay
≥97% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
Cl.Cl.CC(=N)NCCCC[C@H](N)C(O)=O
InChI
1S/C8H17N3O2.2ClH/c1-6(9)11-5-3-2-4-7(10)8(12)13;;/h7H,2-5,10H2,1H3,(H2,9,11)(H,12,13);2*1H/t7-;;/m0../s1
InChI key
OQIBCXRAFAHXMM-KLXURFKVSA-N
Gene Information
human ... NOS2(4843)
Application
L-N6-(1-Iminoethyl)lysine dihydrochloride has been used as an inducible nitric oxide synthase (iNOS) inhibitor:
- to study its effects on leptin-induced modulation of fibronectin type III domain-containing five (FNDC5)/irisin in myocytes and fat cells of murine
- to study its effects on leptin-induced inflammation in hepatocytes
- to block the production of nitric oxide in mice bone marrow mesenchymal stromal cells (BMSCs)
Biochem/physiol Actions
Selective inhibitor of inducible nitric oxide synthase (iNOS).
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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