D2521
(+)-cis-Diltiazem hydrochloride
≥99% (HPLC)
Synonym(s):
(2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride, CRD-401
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SGD 745.00
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About This Item
SGD 745.00
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Assay
≥99% (HPLC)
form
powder
originator
Valeant
storage temp.
2-8°C
SMILES string
Cl.COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O
InChI
1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1
InChI key
HDRXZJPWHTXQRI-BHDTVMLSSA-N
Gene Information
human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779)
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This Item | BP726 | D1980000 | BP899 |
---|---|---|---|
assay ≥99% (HPLC) | assay - | assay - | assay - |
Quality Level 200 | Quality Level - | Quality Level - | Quality Level - |
storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C |
originator Valeant | originator - | originator - | originator - |
Gene Information human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779) | Gene Information human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779) | Gene Information human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779) | Gene Information human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779) |
General description
Application
- to study its effects on diffusion and release in monolithic dispersion matrix(26)
- to study its neuroprotective effects in retinitis pigmentosa (RP) models(27)
- as an antagonist against the Cav1.2 L-type calcium channels (LTCCs)(28)
Biochem/physiol Actions
Features and Benefits
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
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