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About This Item
Linear Formula:
CH3CON(CH3)2
CAS Number:
Molecular Weight:
87.12
Beilstein:
1737614
EC Number:
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.21
grade:
reagent
bp:
164.5-166 °C (lit.)
vapor pressure:
2 mmHg ( 25 °C)
4 mmHg ( 38 °C)
4 mmHg ( 38 °C)
Recommended Products
grade
reagent
Quality Level
vapor density
3 (vs air)
vapor pressure
2 mmHg ( 25 °C)
4 mmHg ( 38 °C)
product line
ReagentPlus®
Assay
99%
form
liquid
autoignition temp.
914 °F
expl. lim.
1.8 %, 100 °F
11.5 %, 160 °F
dilution
(for general lab use)
refractive index
n20/D 1.437 (lit.)
pH
4 (20 °C, 200 g/L)
bp
164.5-166 °C (lit.)
mp
−20 °C (lit.)
density
0.937 g/mL at 25 °C (lit.)
SMILES string
CN(C)C(C)=O
InChI
1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
InChI key
FXHOOIRPVKKKFG-UHFFFAOYSA-N
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General description
N,N-Dimethylacetamide (DMAc) is a water-miscible organic solvent used in the synthesis of styrene′s, vinyl resins, linear polyesters, acrylic fibers, plastics, pesticides, and synthetic leather. Additionally, it is utilized in the production of adhesives, films, and paint. It participates in dehydrogenation, dehydration, halogenation, deprotonation reactions and reductive carbonylation of transition metals. It can also act as catalysts, promoters, halogen/alkoxy or hydroxyl/halogen exchange mediators, reducing agents, and sources of the base.
Application
N,N-Dimethylacetamide can be used as a solvent in the synthesis of:
It can also be used:
- Cellulose-HA (hydroxyapatite) nanocomposites using microcrystalline cellulose, CaCl2, and NaH2PO4.
- 5-hydroxymethylfurfural (HMF) from various carbohydrates and natural biopolymer lignocellulose in the presence of LiCl.
It can also be used:
- In the Pd-catalyzed regioselective synthesis of ketones from olefins using molecular oxygen.
- As a solvent as well as a methylene source in the regioselective linkage of two imidazo[1,2-a] pyridines using Cu(OAc)2 catalyst.
Features and Benefits
N,N-Dimethylacetamide has
- High dissolution power of various substrate.
- High capacity to solvate anions.
Legal Information
Belle Chemical Company
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
Flash Point(F)
147.2 °F - closed cup
Flash Point(C)
64 °C - closed cup
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