195995
2-Thiopheneacetyl chloride
98%
Synonym(s):
2-Thienylacetyl chloride
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About This Item
Empirical Formula (Hill Notation):
C6H5ClOS
CAS Number:
Molecular Weight:
160.62
Beilstein:
114547
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
vapor pressure
4 mmHg ( 83 °C)
Quality Level
Assay
98%
form
liquid
refractive index
n20/D 1.551 (lit.)
bp
105-106 °C/22 mmHg (lit.)
130-135 °C/90 mmHg (lit.)
density
1.303 g/mL at 25 °C (lit.)
functional group
acyl chloride
storage temp.
2-8°C
SMILES string
ClC(=O)Cc1cccs1
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Application
2-Thiopheneacetyl chloride was used in the synthesis of:
- (S)-ethyl-1-(2-thiopheneacetyl)-3-piperidinecarboxylate, nipecotate-containing immunopotentiator
- 5-fluorouracil-cephalosporin prodrug
- series of new N,N′-di(thiopheneacetyl)diamines derivatives
- 6-β-(thiophen-2′-yl)acetamidomorphine
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
215.6 °F - closed cup
Flash Point(C)
102 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Development of an efficient synthesis for a nipecotate-containing immunopotentiator.
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Synthesis and Biological Evaluation of N, N'-di (thiopheneacetyl) diamines Series as Antitubercular Agents.
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An efficient synthesis of a 5-fluorouracil-cephalosporin prodrug is described for use against colorectal and other cancers in antibody and gene-directed therapies. The compound shows stability in aqueous media until specifically activated by beta-lactamase (betaL). The kinetic parameters of the 5-fluorouracil-cephalosporin
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