E4250

(−)-Epinephrine

≥99% (HPLC), powder, adrenoceptor agonist

• Synonym(s): (−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine
• Linear Formula: (HO)₂C₆H₃CH(OH)CH₂NHCH₃
• CAS Number: 51-43-4
• Molecular Weight: 183.20
• Beilstein: 2368277
• EC Number: 200-098-7
• MDL number: MFCD00002204
• UNSPSC Code: 12352200
• PubChem Substance ID: 24894545
• NACRES: NA.77

Properties

• Product Name: (−)-Epinephrine,
• Quality Level: 200
• mp: 215 °C (dec.) (lit.)
• storage temp.: 2-8°C
• SMILES string: CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1
• InChI key: UCTWMZQNUQWSLP-VIFPVBQESA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155) ; rat ... Adra1a(29412), Adra2a(25083), Adrb1(24925), Adrb2(24176), Drd1a(24316), Drd2(24318)

Description

Biochem/physiol Actions

Adrenoceptor agonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and β-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Reconstitution

This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50 mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 + H331,H310
• Precautionary Statements: P261 - P262 - P280 - P301 + P310 - P302 + P352 + P310 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves