Raman spectroscopy is an effective analytical technique for in-line, real-time monitoring of cell culture parameters, requiring a calibration phase that can be resource-intensive and time-consuming. Ready-to-use models directly embedded into the Raman analyzer simplify calibration. Users can bypass extensive model development and begin monitoring for immediate insights.
This webinar presents findings from fed-batch and perfusion cell culture runs utilizing ready-to-use models for in-line, real-time measurement of glucose, lactate and mAb titer. The capabilities of on-line Raman sensor for critical attributes monitoring in downstream & new modalities areas will be also highlighted.
In this webinar, you will learn:
- How plug-and-play models embedded into a Raman analyzer simplify the calibration workflow
- Applications of ready-to-use models in monitoring glucose, lactate, and monoclonal antibody (mAb) titer during cell culture runs
- How the Transfer Learning Algorithms (TLA) refines and improves the initial models
- How to streamline the implementation of Raman technology in Chromatography and Tangential Flow Filtration (TFF)
Speakers

Kevin Grollier
Merck
PAT Implementation & Support Engineer
Kevin Grollier graduated from the Lyon Pharmaceutical Industry Institute (IPIL), with an M.S. in pharmaceutical production specializing in biotechnology. This diploma was reinforced by training at the management school of Lyon. Within our company, he is a PAT Implementation and support engineer in charge of implementing Raman projects at customer sites, training ProCellics™ Raman Analyzer with Bio4C™ PAT Raman software users, and providing customers with technical support on hardware, software, and data analysis topics. Before joining our company, he worked at Merial (now BIAH) as a QA validation engineer where he had the opportunity to work on various items of the validation.
Pharma and biopharma manufacturing
- Pharma and biopharma manufacturing
Duration:1h
Language:English
Session 1:Tue, July 22, 2025 4:00 PM CEST
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