- A novel straightforward synthesis of 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF.
A novel straightforward synthesis of 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF.
Organic letters (2014-06-17)
Xiaowen Xu, Min Zhang, Huanfeng Jiang, Jia Zheng, Yiqun Li
PMID24933098
초록
A novel straightforward synthesis of both symmetrical and unsymmetrical 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF as a one-carbon synthon has been developed. The presented method allows synthesizing the products that are currently inaccessible or challenging to prepare with the advantages of operational simplicity, broad substrate scope, and no need for prefunctionalized reagents, making it a highly practical approach to access various 2,4-disubstituted-1,3,5-triazines.
MATERIALS
제품 번호
브랜드
제품 설명
Copper, tube, 100mm, outside diameter 4.0mm, inside diameter 3.2mm, wall thickness 0.4mm, as drawn, 99.9%
Copper, tube, 200mm, outside diameter 0.75mm, inside diameter 0.23mm, wall thickness 0.26mm, as drawn, 99.9%
Copper - O.F.H.C., foil, 10mm disks, thickness 0.010mm, hard, 99.95+%
Copper - O.F.H.C., foil, 15mm disks, thickness 0.7mm, half hard, 99.95+%
Copper, tube, 500mm, outside diameter 12.7mm, inside diameter 10.26mm, wall thickness 1.22mm, as drawn, 99.9%
Copper, tube, 200mm, outside diameter 2.5mm, inside diameter 1.9mm, wall thickness 0.3mm, as drawn, 99.9%
Copper - O.F.H.C., foil, 50mm disks, thickness 0.7mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 1m coil, thickness 0.025mm, hard, 99.95+%
Copper - O.F.H.C., foil, 1m coil, thickness 0.05mm, hard, 99.95+%
Copper - O.F.H.C., foil, 15mm disks, thickness 0.025mm, hard, 99.95+%
Copper - O.F.H.C., foil, 10m coil, thickness 0.1mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 5m coil, thickness 0.05mm, hard, 99.95+%
Copper - O.F.H.C., foil, 50mm disks, thickness 0.025mm, hard, 99.95+%
Copper - O.F.H.C., foil, 1m coil, thickness 0.1mm, coil width 100mm, hard, 99.95+%
Copper - O.F.H.C., foil, 15mm disks, thickness 0.1mm, hard, 99.95+%
Copper, tube, 200mm, outside diameter 1.75mm, inside diameter 0.33mm, wall thickness 0.71mm, as drawn, 99.9%
Copper - O.F.H.C., foil, 5m coil, thickness 0.25mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 25mm disks, thickness 0.010mm, hard, 99.95+%
Copper - O.F.H.C., foil, 1m coil, thickness 0.075mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 15mm disks, thickness 0.05mm, hard, 99.95+%
Copper, tube, 200mm, outside diameter 10.4mm, inside diameter 10mm, wall thickness 0.2mm, as drawn, 99.9%
Copper, tube, 500mm, outside diameter 6.35mm, inside diameter 4.93mm, wall thickness 0.71mm, as drawn, 99.9%
Copper - O.F.H.C., foil, 5m coil, thickness 0.006mm, hard, 99.95+%
Copper - O.F.H.C., foil, 15mm disks, thickness 0.075mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 25mm disks, thickness 0.5mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 15mm disks, thickness 0.25mm, half hard, 99.95+%
Copper, tube, 500mm, outside diameter 3.5mm, inside diameter 1.56mm, wall thickness 0.97mm, as drawn, 99.9%
Copper - O.F.H.C., foil, 2m coil, thickness 0.075mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 10mm disks, thickness 0.25mm, half hard, 99.95+%
Copper, wire reel, 0.1m, diameter 1.0mm, as drawn, 99.99+%